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CS-W001157 4
Total: USD 88.00

5-Bromo-2-methoxy-4-methylpyrimidine

  • CAS No. 38696-23-0

  • Cat. No. CS-0089427
  • Purity≥98%
  • MDL No.MFCD18410559
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-methoxy-4-methylpyrimidine|CS-0089427

Structure of 38696-23-0

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Description

5-Bromo-2-methoxy-4-methylpyrimidine features a pyrimidine core functionalized with bromo, methoxy, and methyl groups at strategic positions, enabling selective cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and agrochemical scaffolds, offering high reactivity under palladium-catalyzed conditions. The methoxy and methyl substituents enhance solubility and stability during synthetic processing.

Application

5-Bromo-2-methoxy-4-methylpyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic bromine site. The methoxy and methyl groups provide orthogonal functional handles for further derivatization, while the pyrimidine core offers excellent bench stability and compatibility with standard synthetic protocols.

General Information

  • CAS No. 38696-23-0
  • Cat. No. CS-0089427
  • Purity ≥98%
  • MDL No. MFCD18410559
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂O
  • Molecular Weight 203.04
  • Synonym(s) 5-Brom-2-methoxy-4-methylpyrimidin
  • SMILES COC1=NC(C)=C(Br)C=N1

Computational Chemistry Data

  • TPSA   35.01
  • LogP   1.55612
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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