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2-Fluoro-N-methylethan-1-amine hydrochloride

  • CAS No. 3832-36-8

  • Cat. No. CS-0103514
  • Molecule weight113.56
  • Purity≥97%
  • MDL No.MFCD11043108

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-N-methylethan-1-amine hydrochloride|CS-0103514

Structure of 3832-36-8

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General Information

  • CAS No. 3832-36-8
  • Cat. No. CS-0103514
  • Purity ≥97%
  • MDL No. MFCD11043108
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₉ClFN
  • Molecular Weight 113.56
  • Synonym(s) 2-fluoro-N-methylethanamine hydrochloride
  • SMILES FCCNC.[H]Cl

Description

2-Fluoro-N-methylethan-1-amine hydrochloride offers a fluorinated amine handle for synthetic applications, featuring enhanced nucleophilicity and metabolic stability. This bench-stable salt form improves solubility and handling in aqueous reaction systems, enabling efficient incorporation into pharmaceutical intermediates and bioactive molecules.

Application

2-Fluoro-N-methylethan-1-amine hydrochloride serves as a versatile fluorinated building block for medicinal chemistry, enabling the synthesis of bioactive molecules through nucleophilic substitution and amine coupling reactions. Its bench-stable hydrochloride salt form facilitates handling and purification, while the fluorinated ethylamine moiety provides enhanced metabolic stability and favorable pharmacokinetic properties in target-directed synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H226-H302-H318-H331-H341-H360-H370-H371-H372
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P304+P340-P330-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   0.5971
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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