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Structure of 3824-45-1
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4,6-Dichloro-2-fluoropyrimidine serves as a pivotal heterocyclic scaffold in medicinal chemistry, offering enhanced reactivity at the C4 and C6 positions due to orthogonal halogenation. The fluorine atom at C2 imparts electron-withdrawing character, facilitating nucleophilic substitution under mild conditions. This compound integrates efficiently into kinase inhibitors, antiviral agents, and agrochemicals, where its halogenated framework enables precise functionalization and metabolic stability.
4,6-Dichloro-2-fluoropyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds through nucleophilic substitution. Its orthogonal reactivity allows sequential functionalization at C4 and C6 positions, while the 2-fluoro group enhances electrophilicity for regioselective coupling. The compound exhibits excellent bench stability and compatibility with standard reaction conditions, facilitating straightforward purification and integration into API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: