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Structure of 381247-99-0
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Methyl 5-bromo-6-hydroxynicotinate features a brominated pyridine core with complementary hydroxyl and ester functionalities. This bifunctional scaffold enables direct coupling in cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive heterocycles. The molecule exhibits favorable solubility in common organic solvents and stability under standard bench conditions, facilitating its use in medicinal chemistry and process development workflows.
Methyl 5-bromo-6-hydroxynicotinate serves as a versatile building block in heterocyclic synthesis, enabling selective functionalization at the C5 and C6 positions. The bromo group facilitates palladium-catalyzed cross-coupling reactions, while the hydroxyl function supports derivatization or protection strategies. Its bench-stable nature and compatibility with standard purification methods make it well-suited for iterative synthesis workflows in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: