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CS-W001157 4
Total: USD 88.00

4-(Methylsulfonylamino)benzeneboronic acid

  • CAS No. 380430-57-9

  • Cat. No. CS-W002909
  • Purity≥95%
  • MDL No.MFCD02179473

*For research and further manufacturing use only, not for direct human use.

4-(Methylsulfonylamino)benzeneboronic acid|CS-W002909

Structure of 380430-57-9

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General Information

  • CAS No. 380430-57-9
  • Cat. No. CS-W002909
  • Purity ≥95%
  • MDL No. MFCD02179473
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀BNO₄S
  • Molecular Weight 215.04
  • Synonym(s) 4-(Methylsulfonylamino)phenylboronic acid
  • SMILES OB(C1=CC=C(NS(=O)(C)=O)C=C1)O

Application

4-(Methylsulfonylamino)benzeneboronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling the efficient construction of biaryl scaffolds under mild conditions. The methylsulfonylamino group imparts excellent stability and solubility, while the boronic acid functionality offers reliable reactivity with aryl halides and triflates. Its compatibility with diverse functional groups and ease of purification make it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      124-63-0
    • In-stock
      4-Aminophenylboronic acid pinacol ester|CS-M0336
      214360-73-3
    • ~99%
    • In-stock
      4-(Methylsulfonylamino)benzeneboronic acid|CS-W002909
      380430-57-9

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO KG Patent: WO2004/62663 A1, 2004 ; Location in patent: Page/Page column 30 ;

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   86.63
  • LogP   -1.2621
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   3

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