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CS-W001157 4
Total: USD 88.00

Bis-Tos-PEG4

  • CAS No. 37860-51-8

  • Cat. No. CS-W004816
  • Purity≥97%
  • MDL No.MFCD00075239

*For research and further manufacturing use only, not for direct human use.

Bis-Tos-PEG4|CS-W004816

Structure of 37860-51-8

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General Information

  • CAS No. 37860-51-8
  • Cat. No. CS-W004816
  • Purity ≥97%
  • MDL No. MFCD00075239
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₃₀O₉S₂
  • Molecular Weight 502.60
  • Synonym(s) PROTAC Linker 16
  • SMILES O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOS(C2=CC=C(C)C=C2)(=O)=O)=O

Description

Tetraethylene glycol di(p-toluenesulfonate) was used in the preparation of donor-spacer-acceptor podand system, dual channel fluorosensor for Li+, Mg2+ and Ca2+.

Application

Bis-Tos-PEG4 serves as a versatile bifunctional linker for conjugation and polymer synthesis, enabling efficient coupling of biomolecules and small molecules. Its PEG4 spacer provides enhanced solubility and reduced aggregation, while the Tosyl (Tos) groups offer reliable activation for nucleophilic substitution under mild conditions. The molecule demonstrates excellent bench stability and clean reaction profiles, facilitating straightforward purification and integration into established synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   114.43
  • LogP   2.46404
  • H_Acceptors   9
  • H_Donors   0
  • Rotatable_Bonds   16

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