4,5-Dimethyl-1,3-dioxol-2-one

Name: 4,5-Dimethyl-1,3-dioxol-2-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 37830-90-3
Cat. No. CS-W013644
Purity≥98%
MDL No.MFCD00135139

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,5-Dimethyl-1,3-dioxol-2-one|CS-W013644

Structure of 37830-90-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 37830-90-3
Cat. No. CS-W013644
Purity ≥98%
MDL No. MFCD00135139
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₆O₃
Molecular Weight 114.10
Synonym(s) 4,5-dimethyl-1,3-dioxolene-2-one
SMILES CC1=C(OC(O1)=O)C

Description

4,5-Dimethyl-1,3-dioxol-2-one is a bench-stable, moisture-tolerant cyclic carbonate featuring two methyl groups that enhance solubility in polar organic solvents. This electron-deficient heterocycle serves as a selective acylating agent in peptide synthesis and coupling reactions, where its strained ring facilitates nucleophilic attack under mild conditions.

Application

4,5-Dimethyl-1,3-dioxol-2-one serves as a stable, bench-ready synthon for the construction of substituted β-lactones and heterocyclic scaffolds. Its electrophilic carbonyl functionality enables selective reactions with nucleophiles such as amines and alcohols, facilitating the synthesis of functionalized intermediates under mild conditions. The molecule exhibits excellent stability and ease of purification, making it a practical choice for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

Route1
- 75-44-5
- 513-86-0
- ~56%
- In-stock
  
  37830-90-3
References
- E. R. Squibb and Sons, Inc. Patent: US6117885 A1, 2000 ;
Route2
- 32315-10-9
- 513-86-0
- ~42%
- In-stock
  
  37830-90-3
References
- Sahu, Devi Prasad Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 8 p. 1722 - 1723

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.35
LogP 0.84964
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Key Words

4,5-Dimethyl-1,3-dioxol-2-one sigma4,5-Dimethyl-1,3-dioxol-2-one manufacturer4,5-Dimethyl-1,3-dioxol-2-one price4,5-Dimethyl-1,3-dioxol-2-one structure4,5-Dimethyl-1,3-dioxol-2-one SDSbuy 4,5-Dimethyl-1,3-dioxol-2-one4,5-Dimethyl-1,3-dioxol-2-one supplier4,5-Dimethyl-1,3-dioxol-2-one uses4,5-Dimethyl-1,3-dioxol-2-one molecular weightprice of 4,5-Dimethyl-1,3-dioxol-2-one4,5-Dimethyl-1,3-dioxol-2-one chemical name formula of 4,5-Dimethyl-1,3-dioxol-2-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4,5-Dimethyl-1,3-dioxol-2-one

CAS No. 37830-90-3

Recommended Products