Pyrrolidine-2,4-dione

Name: Pyrrolidine-2,4-dione
Brand: ChemScene
Availability: InStock
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CAS No. 37772-89-7
Cat. No. CS-0048723
Purity≥96%
MDL No.MFCD11110992

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 37772-89-7

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Description

Pyrrolidine-2,4-dione delivers a rigid, electron-deficient scaffold ideal for constructing bioactive heterocycles. This bench-stable diketone features enhanced reactivity in nucleophilic additions and serves as a key intermediate in synthesizing pharmaceuticals and functional materials.

Application

Pyrrolidine-2,4-dione serves as a versatile scaffold in synthetic organic chemistry, enabling efficient construction of heterocyclic frameworks through well-established Michael additions and cycloaddition reactions. Its inherent electrophilic character at C2 and C4 facilitates regioselective functionalization, while the molecule exhibits favorable bench stability and ease of purification. This compound functions as a key building block in the synthesis of bioactive molecules, particularly within medicinal chemistry campaigns targeting kinase inhibitors and other pharmaceutical intermediates.

General Information

CAS No. 37772-89-7
Cat. No. CS-0048723
Purity ≥96%
MDL No. MFCD11110992
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₅NO₂
Molecular Weight 99.09
Synonym(s) 2,4-Pyrrolidinedione
SMILES O=C1CNC(=O)C1

Computational Chemistry Data

TPSA 46.17
LogP -0.9246
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Pyrrolidine-2,4-dione

CAS No. 37772-89-7

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