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CS-W001157 4
Total: USD 88.00

4-Hydroxy-2-pyrrolidone

  • CAS No. 25747-41-5

  • Cat. No. CS-W018808
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-2-pyrrolidone|CS-W018808

Structure of 25747-41-5

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General Information

  • CAS No. 25747-41-5
  • Cat. No. CS-W018808
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂
  • Molecular Weight 101.10
  • Synonym(s) 4-hydroxypyrrolidin-2-one
  • SMILES O=C1NCC(O)C1

Description

4-Hydroxy-2-pyrrolidone is a stable, moisture-tolerant heterocycle featuring a hydroxyl group at the 4-position and a lactam carbonyl at the 2-position. This functionalized pyrrolidone integrates readily into synthetic sequences requiring polar, hydrogen-bonding motifs. Its bench-stable nature supports reliable use in diverse reaction environments.

Application

4-Hydroxy-2-pyrrolidone serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrrolidine-based scaffolds. Its hydroxyl and lactam functionalities offer orthogonal reactivity for derivatization, while the molecule exhibits excellent bench stability and compatibility with standard synthetic protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -1.1328
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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