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CS-W001157 4
Total: USD 88.00

5-Chloro-1,3,4-thiadiazol-2-amine

  • CAS No. 37566-40-8

  • Cat. No. CS-W005658
  • Purity≥96%
  • MDL No.MFCD01578280

*For research and further manufacturing use only, not for direct human use.

5-Chloro-1,3,4-thiadiazol-2-amine|CS-W005658

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General Information

  • CAS No. 37566-40-8
  • Cat. No. CS-W005658
  • Purity ≥96%
  • MDL No. MFCD01578280
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₂ClN₃S
  • Molecular Weight 135.58
  • Synonym(s) 5-Chloro-1,3,4-thiadiazol-2-ylamine
  • SMILES NC1=NN=C(Cl)S1

Description

5-Chloro-1,3,4-thiadiazol-2-amine features a chlorinated thiadiazole core with a primary amine group, delivering enhanced reactivity for heterocyclic functionalization. This bench-stable scaffold integrates readily into bioactive molecule design, particularly in agrochemical and pharmaceutical applications, where its electron-deficient ring system supports targeted interactions.

Application

5-Chloro-1,3,4-thiadiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its chloro substituent enables electrophilic functionalization, while the thiadiazole core offers robust stability and favorable electronic properties. The amine group facilitates coupling reactions, including amidation and alkylation, supporting diverse derivatization strategies. This compound demonstrates excellent bench stability and compatibility with standard purification methods, making it a reliable reagent for constructing bioactive scaffolds and functionalized polymers.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   0.7737
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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