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CS-W001157 4
Total: USD 88.00

5-(Trifluoromethyl)-1,3,4-thiadiazol-2-amine

  • CAS No. 10444-89-0

  • Cat. No. CS-D0490
  • Purity≥96%
  • MDL No.MFCD00003109

*For research and further manufacturing use only, not for direct human use.

5-(Trifluoromethyl)-1,3,4-thiadiazol-2-amine|CS-D0490

Structure of 10444-89-0

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General Information

  • CAS No. 10444-89-0
  • Cat. No. CS-D0490
  • Purity ≥96%
  • MDL No. MFCD00003109
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₂F₃N₃S
  • Molecular Weight None
  • Synonym(s) 2-Amino-5-trifluoromethyl-1,3,4-thiadiazole
  • SMILES FC(C1=NN=C(N)S1)(F)F

Description

2-Amino-5-trifluoromethyl-1,3,4-thiadiazole was used in the synthesis of:series of 2-sulfonamido/trifluoromethyl-6-(4-substituted aryl/heteroaryl)imidazo[2,1-b]-1,3,4-thiadiazole derivatives2-trifluoromethyl/sulfonamido-5,6-diarylsubstituted imidazo[2,1-b]-1,3,4-thiadiazole derivativesbicyclic bridgehead itrogen heterocycles

Synthesis

  • Route1
    • In-stock
      Thiosemicarbazide|CS-0008325
      79-19-6
    • null|null
      407-25-0
    • ~82%
    • In-stock
      5-(Trifluoromethyl)-1,3,4-thiadiazol-2-amine|CS-D0490
      10444-89-0

    References

    • Alegaon, Shankar G.; Alagawadi, Kallanagouda R. Medicinal Chemistry Research, 2012 , vol. 21, # 6 p. 816 - 824
  • Route2
    • In-stock
      Thiosemicarbazide|CS-0008325
      79-19-6
    • null|null
      76-05-1
    • ~82%
    • In-stock
      5-(Trifluoromethyl)-1,3,4-thiadiazol-2-amine|CS-D0490
      10444-89-0

    References

    • Boechat, Nubia; Ferreira, Sabrina B.; Glidewell, Christopher; Low, John N.; Skakle, Janet M.S.; Wardell, Solange M.S.V. Acta Crystallographica Section C: Crystal Structure Communications, 2006 , vol. 62, # 1 p. o42-o44
  • Route3

    References

    • Fennewald, James C.; Lipshutz, Bruce H. Green Chemistry, 2014 , vol. 16, # 3 p. 1097 - 1100

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.1391
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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