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Structure of 37519-09-8
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4-(Trifluoromethyl)benzene-1,2-diol features a sterically accessible catechol core appended with a strongly electron-withdrawing trifluoromethyl group. This combination imparts enhanced stability and tailored reactivity in oxidation-sensitive transformations. The molecule serves as a key scaffold for bioactive compound synthesis and functional materials development under standard bench conditions.
4-(Trifluoromethyl)benzene-1,2-diol serves as a versatile ortho-dihydroxy building block for the synthesis of complex heterocycles and bioactive scaffolds. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the adjacent phenolic hydroxyls enable facile oxidation to quinones or coordination in transition metal-catalyzed coupling reactions. The compound exhibits good bench stability and is compatible with standard protecting group strategies, facilitating its use in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: