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CS-W001157 4
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Benzyl 1-methylhydrazinecarboxylate

  • CAS No. 37519-04-3

  • Cat. No. CS-W022587
  • Purity≥97%
  • MDL No.MFCD21604061

*For research and further manufacturing use only, not for direct human use.

Benzyl 1-methylhydrazinecarboxylate|CS-W022587

Structure of 37519-04-3

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General Information

  • CAS No. 37519-04-3
  • Cat. No. CS-W022587
  • Purity ≥97%
  • MDL No. MFCD21604061
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O₂
  • Molecular Weight 180.20
  • Synonym(s) Hydrazinecarboxylic acid, 1-methyl-, phenylmethyl ester
  • SMILES NN(C(OCC1=CC=CC=C1)=O)C

Description

Benzyl 1-methylhydrazinecarboxylate features a hydrazinecarboxylate core with a methylated nitrogen and benzyl ester group, enabling selective reactivity in synthetic transformations. This bench-stable compound integrates readily into peptide-like scaffolds and serves as a masked hydrazine source under mild conditions.

Application

Benzyl 1-methylhydrazinecarboxylate serves as a reliable hydrazine-based building block for heterocyclic synthesis, enabling efficient access to pyrazole and triazole scaffolds under mild conditions. Its benzyl ester functionality offers excellent bench stability and facile deprotection via hydrogenolysis, while the methylhydrazine moiety exhibits predictable reactivity in cycloaddition and condensation reactions. This compound functions as a versatile intermediate in medicinal chemistry campaigns requiring nitrogen-rich core structures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.1287
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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