Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Boc-5-iodoindole

  • CAS No. 374818-66-3

  • Cat. No. CS-0212134
  • Purity≥96%
  • MDL No.MFCD09258644

*For research and further manufacturing use only, not for direct human use.

1-Boc-5-iodoindole|CS-0212134

Structure of 374818-66-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 374818-66-3
  • Cat. No. CS-0212134
  • Purity ≥96%
  • MDL No. MFCD09258644
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₄INO₂
  • Molecular Weight 343.16
  • Synonym(s) tert-Butyl 5-iodo-1H-indole-1-carboxylate
  • SMILES CC(C)(C)OC(=O)N1C=CC2=CC(=CC=C21)I

Description

1-Boc-5-iodoindole features a sterically protected indole scaffold with a reactive iodine handle at the 5-position, enabling direct coupling in cross-coupling transformations. The Boc group ensures stability during storage and handling, while the iodide facilitates efficient palladium-catalyzed functionalization under standard conditions.

Application

1-Boc-5-iodoindole serves as a versatile building block for the synthesis of functionalized indole derivatives, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. The Boc group provides stability and ease of deprotection under mild acidic conditions, while the iodine substituent facilitates reliable C–C bond formation in standard Suzuki, Stille, or Negishi couplings. Its bench-stable nature and predictable reactivity make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and process R&D workflows.

Synthesis

  • Route1

    References

    • ABBOTT LABORATORIES Patent: WO2007/76034 A2, 2007 ; Location in patent: Page/Page column 122 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   31.23
  • LogP   4.0291
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Boc-5-iodoindole sigma1-Boc-5-iodoindole manufacturer1-Boc-5-iodoindole price1-Boc-5-iodoindole structure1-Boc-5-iodoindole SDSbuy 1-Boc-5-iodoindole1-Boc-5-iodoindole supplier1-Boc-5-iodoindole uses1-Boc-5-iodoindole molecular weightprice of 1-Boc-5-iodoindole1-Boc-5-iodoindole chemical name formula of 1-Boc-5-iodoindole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label