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tert-Butyl 5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate

  • CAS No. 374795-76-3

  • Cat. No. CS-0041989
  • Purity≥97%
  • MDL No.MFCD19707617

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate|CS-0041989

Structure of 374795-76-3

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General Information

  • CAS No. 374795-76-3
  • Cat. No. CS-0041989
  • Purity ≥97%
  • MDL No. MFCD19707617
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N₃O₂
  • Molecular Weight 223.27
  • Synonym(s) None
  • SMILES O=C(N1CC2=CN=CN2CC1)OC(C)(C)C

Description

tert-Butyl 5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a fused imidazopyrazine core. This compound integrates readily into medicinal chemistry campaigns, enabling direct access to nitrogen-rich scaffolds through mild deprotection. The tert-butyl ester group facilitates purification and handling while supporting downstream functionalization.

Application

tert-Butyl 5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylate serves as a versatile scaffold for constructing bioactive heterocycles, enabling efficient functionalization at the pyrazine core. The protected amine and carboxylate groups offer orthogonal reactivity, facilitating downstream derivatization via standard coupling and reduction protocols. Bench-stable and readily purified by chromatography, it functions effectively in medicinal chemistry campaigns targeting kinase inhibitors and CNS-directed therapeutics.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   47.36
  • LogP   1.6338
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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