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CS-W001157 4
Total: USD 88.00

2-Chloromethylchinoline hydrochloride

  • CAS No. 3747-74-8

  • Cat. No. CS-W023193
  • Purity≥97%
  • MDL No.MFCD00012734
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloromethylchinoline hydrochloride|CS-W023193

Structure of 3747-74-8

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Description

2-Chloromethylchinoline hydrochloride delivers a reactive chloromethyl handle at the 2-position of a chinoline scaffold, enabling site-specific conjugation in synthetic and medicinal chemistry. This bench-stable salt features enhanced solubility in aqueous and polar organic media, facilitating efficient coupling reactions under mild conditions.

Application

2-Chloromethylchinoline hydrochloride serves as a versatile synthetic building block for the construction of bioactive heterocycles and pharmaceutical intermediates. The chloromethyl group enables efficient nucleophilic substitution reactions, facilitating the introduction of diverse side chains under mild conditions. Its bench-stable hydrochloride salt form enhances handling and solubility in common organic solvents, supporting reliable performance in multi-step synthesis and scale-up applications.

General Information

  • CAS No. 3747-74-8
  • Cat. No. CS-W023193
  • Purity ≥97%
  • MDL No. MFCD00012734
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉Cl₂N
  • Molecular Weight 214.09
  • Synonym(s) 2-(Chloromethyl)quinoline hydrochloride; 2-(Chloromethyl)quinoline monohydrochloride; alpha-Chloroquinaldine hydrochloride
  • SMILES ClCC1=NC2=CC=CC=C2C=C1.[H]Cl

Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.3954
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group :
Hazard Statements : H302-H315-H317-H318
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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