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CS-W001157 4
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2-(Pyrrolidin-1-yl)acetic acid

  • CAS No. 37386-15-5

  • Cat. No. CS-W020371
  • Molecule weight129.16
  • Purity≥95%
  • MDL No.MFCD04114075

*For research and further manufacturing use only, not for direct human use.

2-(Pyrrolidin-1-yl)acetic acid|CS-W020371

Structure of 37386-15-5

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General Information

  • CAS No. 37386-15-5
  • Cat. No. CS-W020371
  • Purity ≥95%
  • MDL No. MFCD04114075
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) Pyrrolidin-1-ylacetic acid
  • SMILES O=C(CN1CCCC1)O

Description

2-(Pyrrolidin-1-yl)acetic acid features a pyrrolidine ring linked to a carboxylic acid moiety, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for targeted ligand design.

Application

2-(Pyrrolidin-1-yl)acetic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through its reactive carboxylic acid and amine-functionalized side chain. The pyrrolidinyl group enhances solubility and metabolic stability, while the molecule exhibits excellent bench stability and compatibility with standard coupling protocols. It functions effectively in peptide extension, macrocyclization, and heterocycle synthesis, offering predictable reactivity and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   0.1668
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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