Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Cyano-2-methyl-benzenesulfonylchloride

  • CAS No. 372198-49-7

  • Cat. No. CS-0130481
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Cyano-2-methyl-benzenesulfonylchloride|CS-0130481

Structure of 372198-49-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 372198-49-7
  • Cat. No. CS-0130481
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆ClNO₂S
  • Molecular Weight 215.66
  • Synonym(s) 5-Cyano-2-methylbenzene-1-sulfonyl chloride
  • SMILES O=S(C1=CC(C#N)=CC=C1C)(Cl)=O

Description

5-Cyano-2-methyl-benzenesulfonyl chloride features a sulfonyl chloride group flanked by a cyano substituent and a methyl group on the aromatic ring. This electron-deficient architecture enables efficient coupling reactions in synthetic workflows, particularly for installing sulfonamide linkages under mild conditions. The ortho-methyl group provides steric stabilization, enhancing reactivity control and handling stability.

Application

5-Cyano-2-methyl-benzenesulfonyl chloride serves as a versatile sulfonylating agent for the efficient installation of sulfonamide functionalities in medicinal chemistry and agrochemical synthesis. Its ortho-methyl and meta-cyano substituents enhance reactivity while maintaining bench stability, enabling clean transformations with amines under mild conditions. The molecule exhibits excellent functional group tolerance and facilitates straightforward purification, making it ideal for constructing complex heterocyclic scaffolds and sulfonamide-containing APIs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   57.93
  • LogP   1.7942
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Cyano-2-methyl-benzenesulfonylchloride sigma5-Cyano-2-methyl-benzenesulfonylchloride manufacturer5-Cyano-2-methyl-benzenesulfonylchloride price5-Cyano-2-methyl-benzenesulfonylchloride structure5-Cyano-2-methyl-benzenesulfonylchloride SDSbuy 5-Cyano-2-methyl-benzenesulfonylchloride5-Cyano-2-methyl-benzenesulfonylchloride supplier5-Cyano-2-methyl-benzenesulfonylchloride uses5-Cyano-2-methyl-benzenesulfonylchloride molecular weightprice of 5-Cyano-2-methyl-benzenesulfonylchloride5-Cyano-2-methyl-benzenesulfonylchloride chemical name formula of 5-Cyano-2-methyl-benzenesulfonylchloride
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label