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CS-W001157 4
Total: USD 88.00

tert-Butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate

  • CAS No. 370882-66-9

  • Cat. No. CS-0048665
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate|CS-0048665

Structure of 370882-66-9

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General Information

  • CAS No. 370882-66-9
  • Cat. No. CS-0048665
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈N₂O₂
  • Molecular Weight 198.26
  • Synonym(s) None
  • SMILES [H][C@]12CN(C(=O)OC(C)(C)C)[C@@]1([H])CNC2

Description

tert-Butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate is a sterically hindered, bench-stable chiral diamine scaffold featuring a rigid bicyclic core that enables precise spatial control in asymmetric synthesis. The protected amine functionality facilitates modular derivatization while maintaining configurational integrity. This scaffold integrates efficiently into catalyst systems and ligand architectures requiring defined nitrogen geometry and enhanced stability under standard reaction conditions.

Application

tert-Butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate serves as a conformationally restricted diamine building block, enabling the synthesis of bioactive heterocycles through established coupling and cyclization protocols. Its bench-stable tert-butyl ester facilitates purification and functional group manipulation, while the rigid bicyclic scaffold provides predictable stereochemical control in medicinal chemistry campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   0.8251
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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