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CS-W001157 4
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(2-Bromoethyl)trimethylsilane

  • CAS No. 18156-67-7

  • Cat. No. CS-0239787
  • Purity≥95%
  • MDL No.MFCD03093623

*For research and further manufacturing use only, not for direct human use.

(2-Bromoethyl)trimethylsilane|CS-0239787

Structure of 18156-67-7

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General Information

  • CAS No. 18156-67-7
  • Cat. No. CS-0239787
  • Purity ≥95%
  • MDL No. MFCD03093623
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃BrSi
  • Molecular Weight 181.15
  • Synonym(s) 2-(TRIMETHYLSILYL)ETHYL BROMIDE
  • SMILES C[Si](C)(C)CCBr

Description

(2-Bromoethyl)trimethylsilane delivers a reactive bromoethyl handle tethered to a stable trimethylsilyl group, enabling efficient silicon-directed functionalization. This bench-stable reagent facilitates site-selective derivatization in synthetic and bioconjugation workflows.

Application

(2-Bromoethyl)trimethylsilane serves as a versatile silyl-protected bromoethyl building block, enabling efficient introduction of reactive bromoalkyl handles under mild conditions. Its trimethylsilyl group provides enhanced stability and facilitates selective deprotection, while the terminal bromide supports reliable coupling reactions with nucleophiles, including amines and thiols. This reagent functions effectively in the synthesis of heterocyclic scaffolds and functionalized intermediates, offering predictable reactivity and ease of purification in standard organic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2924
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H225-H314
Precautionary Statements : P210-P233-P240-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.7195
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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