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CS-W001157 4
Total: USD 88.00

5-Methoxy-1H-benzo[d]imidazole-2-thiol Esomeprazole Impurity

  • CAS No. 37052-78-1

  • Cat. No. CS-0166987
  • Purity≥95%
  • MDL No.MFCD00134581

*For research and further manufacturing use only, not for direct human use.

5-Methoxy-1H-benzo[d]imidazole-2-thiol Esomeprazole Impurity|CS-0166987

Structure of 37052-78-1

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General Information

  • CAS No. 37052-78-1
  • Cat. No. CS-0166987
  • Purity ≥95%
  • MDL No. MFCD00134581
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂OS
  • Molecular Weight None
  • Synonym(s) 5-Methoxy-2-benzimidazolethiol
  • SMILES S=C1NC2=CC(OC)=CC=C2N1

Synthesis

  • Route1
    • null|null
      75-15-0
    • N-(2-Amino-4-methoxyphenyl)acetamide|CS-0153982
      5472-37-7
    • ~%
    • 5-Methoxy-1H-benzo[d]imidazole-2-thiol Esomeprazole Impurity|CS-0166987
      37052-78-1

    References

    • IPCA LABORATORIES LIMITED Patent: WO2004/92142 A1, 2004 ; Location in patent: Page 10 ;
  • Route2
    • 4-Methoxybenzene-1,2-diamine hydrochloride|CS-0339529
      106658-14-4
    • ~%
    • 5-Methoxy-1H-benzo[d]imidazole-2-thiol Esomeprazole Impurity|CS-0166987
      37052-78-1

    References

    • The Upjohn Company Patent: US5077407 A1, 1991 ;
  • Route3
    • null|null
      75-15-0
    • 4-Methoxy-1,2-benzenediamine|CS-W001175
      102-51-2
    • ~74%
    • 5-Methoxy-1H-benzo[d]imidazole-2-thiol Esomeprazole Impurity|CS-0166987
      37052-78-1

    References

    • Joshi, Deepkumar; Parikh, Kalpesh Medicinal Chemistry Research, 2014 , vol. 23, # 3 p. 1290 - 1299

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   40.81
  • LogP   2.23409
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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