Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Methoxy-2-benzimidazolethiol

  • CAS No. 37052-78-1

  • Cat. No. CS-W008378
  • Purity≥98%
  • MDL No.MFCD00134581

*For research and further manufacturing use only, not for direct human use.

5-Methoxy-2-benzimidazolethiol|CS-W008378

Structure of 37052-78-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 37052-78-1
  • Cat. No. CS-W008378
  • Purity ≥98%
  • MDL No. MFCD00134581
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂OS
  • Molecular Weight None
  • Synonym(s) None
  • SMILES COC1=CC(N2)=C(NC2=S)C=C1

Description

5-Methoxy-2-benzimidazolethiol is a hetercocyclic building block. Iodimetric quantification of 5-methoxy-2-benzimidazolethiol in basic medium has been investigated.5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[-1,2-bis(diphenylphosphino)ethane]-1:22P:P;1:32P:P;2:32P:P-di--bromido-1:24Br:Br-bromido-3Br-tricopper(I) acetone hemisolvate.

Application

5-Methoxy-2-benzimidazolethiol serves as a versatile building block for the synthesis of benzimidazole-based heterocycles, enabling efficient derivatization via thiol functional group reactivity. Its bench-stable nature and compatibility with standard coupling protocols facilitate straightforward incorporation into pharmaceutical intermediates and agrochemical scaffolds. The methoxy substituent enhances solubility and modulates electronic properties, supporting diverse synthetic transformations in medicinal chemistry workflows.

Synthesis

  • Route1
    • null|null
      75-15-0
    • N-(2-Amino-4-methoxyphenyl)acetamide|CS-0153982
      5472-37-7
    • ~%
    • In-stock
      5-Methoxy-2-benzimidazolethiol|CS-W008378
      37052-78-1

    References

    • IPCA LABORATORIES LIMITED Patent: WO2004/92142 A1, 2004 ; Location in patent: Page 10 ;
  • Route2
    • 4-Methoxybenzene-1,2-diamine hydrochloride|CS-0339529
      106658-14-4
    • ~%
    • In-stock
      5-Methoxy-2-benzimidazolethiol|CS-W008378
      37052-78-1

    References

    • The Upjohn Company Patent: US5077407 A1, 1991 ;
  • Route3
    • null|null
      75-15-0
    • 4-Methoxy-1,2-benzenediamine|CS-W001175
      102-51-2
    • ~74%
    • In-stock
      5-Methoxy-2-benzimidazolethiol|CS-W008378
      37052-78-1

    References

    • Joshi, Deepkumar; Parikh, Kalpesh Medicinal Chemistry Research, 2014 , vol. 23, # 3 p. 1290 - 1299

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   40.81
  • LogP   2.23409
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Methoxy-2-benzimidazolethiol sigma5-Methoxy-2-benzimidazolethiol manufacturer5-Methoxy-2-benzimidazolethiol price5-Methoxy-2-benzimidazolethiol structure5-Methoxy-2-benzimidazolethiol SDSbuy 5-Methoxy-2-benzimidazolethiol5-Methoxy-2-benzimidazolethiol supplier5-Methoxy-2-benzimidazolethiol uses5-Methoxy-2-benzimidazolethiol molecular weightprice of 5-Methoxy-2-benzimidazolethiol5-Methoxy-2-benzimidazolethiol chemical name formula of 5-Methoxy-2-benzimidazolethiol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label