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Structure of 3704-28-7
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Methyl 2-(methylthio)benzoate features a methylthio group ortho to the ester functionality, delivering enhanced electron density at the aromatic ring. This structural motif enables efficient coupling in transition-metal-catalyzed cross-coupling reactions. The compound exhibits excellent bench stability and solubility in common organic solvents, facilitating straightforward handling in synthetic workflows.
Methyl 2-(methylthio)benzoate serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the ortho position relative to the ester group. Its methylthio substituent offers moderate stability and compatibility with standard reaction conditions, facilitating subsequent transformations such as oxidation to sulfone, electrophilic substitution, or transition-metal-catalyzed coupling processes. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: