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CS-W001157 4
Total: USD 88.00

trans-4-Aminocyclohexanecarboxylic acid

  • CAS No. 3685-25-4

  • Cat. No. CS-W008392
  • Purity≥97%
  • MDL No.MFCD00209953

*For research and further manufacturing use only, not for direct human use.

trans-4-Aminocyclohexanecarboxylic acid|CS-W008392

Structure of 3685-25-4

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General Information

  • CAS No. 3685-25-4
  • Cat. No. CS-W008392
  • Purity ≥97%
  • MDL No. MFCD00209953
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) (1α)-4β-Aminocyclohexanecarboxylic acid
  • SMILES N[C@H]1CC[C@@H](CC1)C(O)=O

Description

trans-4-Aminocyclohexanecarboxylic acid features a rigid, bench-stable cyclohexane scaffold with a strategically positioned amino group and carboxylic acid moiety. This configuration enables direct incorporation into peptide mimetics and bioactive scaffolds where conformational constraint enhances target affinity and metabolic stability.

Application

trans-4-Aminocyclohexanecarboxylic acid serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptidomimetics. Its stable trans configuration and orthogonal functional groups facilitate efficient derivatization, including amide coupling and cyclization reactions. The compound exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput screening campaigns and process-scale synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.5885
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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