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CS-W001157 4
Total: USD 88.00

1-Bromo-9H-fluoren-9-one

  • CAS No. 36804-63-4

  • Cat. No. CS-0162570
  • Purity≥98%
  • MDL No.MFCD09966028

*For research and further manufacturing use only, not for direct human use.

1-Bromo-9H-fluoren-9-one|CS-0162570

Structure of 36804-63-4

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General Information

  • CAS No. 36804-63-4
  • Cat. No. CS-0162570
  • Purity ≥98%
  • MDL No. MFCD09966028
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₇BrO
  • Molecular Weight 259.10
  • Synonym(s) 1-Brom-fluoren-9-on
  • SMILES O=C1C2=C(C3=C1C=CC=C3)C=CC=C2Br

Description

Chlorodimethylphenylsilane is used in the synthesis of enantioenriched allenylsilanes through an ortho-ester Claisen rearrangement of chiral and silylpropargylic alcohols.

Application

1-Bromo-9H-fluoren-9-one serves as a versatile building block in synthetic organic chemistry, enabling efficient C–C and C–heteroatom bond formations via nucleophilic substitution at the bromine site. The fluorenone core provides enhanced stability and facilitates purification, while the ketone functionality supports subsequent transformations including enolate derivatization and reductive coupling. Its bench-stable crystalline form and compatibility with standard reaction conditions make it well-suited for medicinal chemistry campaigns and materials synthesis.

Synthesis

  • Route1
    • [1,1'-Biphenyl]-2-carboxylic acid Conivaptan Impurity|CS-0214024
      947-84-2
    • ~49%
    • In-stock
      1-Bromo-9H-fluoren-9-one|CS-0162570
      36804-63-4

    References

    • Tilly, David; Samanta, Subhendu S.; Castanet, Anne-Sophie; De, Asish; Mortier, Jacques European Journal of Organic Chemistry, 2006 , # 1 p. 174 - 182
  • Route2
    • 9-Fluorenone-1-carboxylic acid|CS-0204780
      1573-92-8
    • ~63%
    • In-stock
      1-Bromo-9H-fluoren-9-one|CS-0162570
      36804-63-4

    References

    • Bronstein, Hindy E.; Choi, Neil; Scott, Lawrence T. Journal of the American Chemical Society, 2002 , vol. 124, # 30 p. 8870 - 8875
  • Route3
    • 3-Bromobiphenyl-2-carboxylic acid|CS-0059851
      94654-52-1
    • ~93%
    • In-stock
      1-Bromo-9H-fluoren-9-one|CS-0162570
      36804-63-4

    References

    • Tilly, David; Samanta, Subhendu S.; Castanet, Anne-Sophie; De, Asish; Mortier, Jacques European Journal of Organic Chemistry, 2006 , # 1 p. 174 - 182

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.6605
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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