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CS-W001157 4
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1H-Pyrazole-3-carbonitrile

  • CAS No. 36650-74-5

  • Cat. No. CS-W019604
  • Purity≥96%
  • MDL No.MFCD08669496

*For research and further manufacturing use only, not for direct human use.

1H-Pyrazole-3-carbonitrile|CS-W019604

Structure of 36650-74-5

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General Information

  • CAS No. 36650-74-5
  • Cat. No. CS-W019604
  • Purity ≥96%
  • MDL No. MFCD08669496
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃N₃
  • Molecular Weight 93.09
  • Synonym(s) Pyrazole-3-carbonitrile
  • SMILES N#CC1=NNC=C1

Description

1H-Pyrazole-3-carbonitrile features a nitrogen-rich heterocyclic core paired with a nitrile group at the 3-position, enabling versatile coupling reactions. This bench-stable compound integrates readily into synthetic sequences requiring electron-deficient aromatic scaffolds.

Application

1H-Pyrazole-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through electrophilic and nucleophilic transformations. Its nitrile group facilitates downstream functionalization via hydrolysis, reduction, or cyclization, while the pyrazole core provides structural rigidity and hydrogen-bonding capacity. The compound exhibits excellent bench stability and compatibility with standard synthetic workflows, supporting its use in API development and combinatorial library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.47
  • LogP   0.28138
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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