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CS-W001157 4
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2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid Doxazosin Impurity

  • CAS No. 3663-80-7

  • Cat. No. CS-0228951
  • Purity≥98%
  • MDL No.MFCD00084888

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid Doxazosin  Impurity|CS-0228951

Structure of 3663-80-7

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General Information

  • CAS No. 3663-80-7
  • Cat. No. CS-0228951
  • Purity ≥98%
  • MDL No. MFCD00084888
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈O₄
  • Molecular Weight 180.16
  • Synonym(s) None
  • SMILES OC(C1COC2=CC=CC=C2O1)=O

Synthesis

  • Route1

    References

    • Rouf, Abdul; Gupta, Pankaj; Aga, Mushtaq A.; Kumar, Brijesh; Chaubey, Asha; Parshad, Rajinder; Taneja, Subhash C. Tetrahedron Asymmetry, 2012 , vol. 23, # 22-23 p. 1615 - 1623
  • Route2
    • 2-Cyano-1,4-benzodioxan|CS-0034639
      1008-92-0
    • ~98%
    • 2,3-Dihydrobenzo[b][1,4]dioxine-2-carboxylic acid Doxazosin  Impurity|CS-0228951
      3663-80-7

    References

    • Tomiyama; Wakabayashi; Yokota Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1988 - 1996
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 77, p. 5373

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.911
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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