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CS-W001157 4
Total: USD 88.00

tert-Butyl (hydroxymethyl)carbamate

  • CAS No. 365572-48-1

  • Cat. No. CS-0619922
  • Molecule weight147.17
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (hydroxymethyl)carbamate|CS-0619922

Structure of 365572-48-1

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General Information

  • CAS No. 365572-48-1
  • Cat. No. CS-0619922
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₃
  • Molecular Weight 147.17
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCO

Description

tert-Butyl (hydroxymethyl)carbamate delivers a protected hydroxymethyl group ideal for iterative synthesis. This bench-stable, moisture-tolerant reagent integrates seamlessly into peptide and small-molecule workflows, enabling selective functionalization without side reactions. The tert-butyl carbamate moiety ensures mild deprotection under acidic conditions.

Application

tert-Butyl (hydroxymethyl)carbamate serves as a stable, bench-friendly amino protecting group that enables selective N-alkylation and subsequent deprotection under mild acidic conditions. Its hydroxymethyl functionality allows for further derivatization via oxidation to aldehyde or carboxylic acid, facilitating access to diverse peptide mimetics and heterocyclic scaffolds. The robust tert-butyl carbamate moiety offers excellent functional group tolerance and ease of purification in multi-step synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   0.4609
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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