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Structure of 364-75-0
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1-Fluoro-4-iodo-2-nitrobenzene features a trifunctional aromatic core with complementary reactivity for cross-coupling and nucleophilic substitution. The electron-deficient ring enables efficient palladium-catalyzed coupling, while the fluorine and iodine positions offer orthogonal functionalization pathways. This compound serves as a versatile scaffold in medicinal chemistry and materials synthesis.
1-Fluoro-4-iodo-2-nitrobenzene serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The ortho-nitro group enhances regioselectivity in coupling events, while the fluoro and iodo substituents provide orthogonal reactivity profiles. Bench-stable and compatible with standard synthetic workflows, it facilitates the synthesis of complex heterocycles and functionalized aryl systems relevant to pharmaceutical development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: