Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Iodo-2-nitrophenol

  • CAS No. 21784-73-6

  • Cat. No. CS-0202570
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Iodo-2-nitrophenol|CS-0202570

Structure of 21784-73-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 21784-73-6
  • Cat. No. CS-0202570
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄INO₃
  • Molecular Weight 265.01
  • Synonym(s) 2-nitro-4-iodophenol
  • SMILES OC1=CC=C(I)C=C1[N+]([O-])=O

Description

4-Iodo-2-nitrophenol features a para-iodo and ortho-nitro substitution on the phenolic ring, creating a highly functionalized aromatic scaffold. This arrangement enables direct coupling in cross-coupling reactions and facilitates downstream derivatization. The molecule exhibits enhanced reactivity due to the electron-withdrawing nitro group adjacent to the hydroxyl, while the iodine serves as a robust handle for palladium-catalyzed transformations. Bench-stable and moisture-tolerant, it supports reliable use in synthetic workflows requiring precision and reproducibility.

Application

4-Iodo-2-nitrophenol serves as a versatile building block in the synthesis of functionalized heterocycles and pharmaceutical intermediates. The iodine group enables palladium-catalyzed cross-coupling reactions, while the ortho-nitro group facilitates selective reductions and subsequent cyclizations. Its stability under standard bench conditions and compatibility with diverse reaction protocols make it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      88-75-5
    • ~90%
    • In-stock
      4-Iodo-2-nitrophenol|CS-0202570
      21784-73-6
    • In-stock
      2-Iodo-6-nitrophenol|CS-0148052
      13073-26-2

    References

    • Synthetic Communications, , vol. 32, # 15 p. 2319 - 2324
  • Route2
    • null|null
      540-38-5
    • ~54%
    • In-stock
      4-Iodo-2-nitrophenol|CS-0202570
      21784-73-6

    References

    • Wang, Liu-Gang; Li, Zhan-Ting Synlett, 2009 , # 3 p. 384 - 389
  • Route3
    • null|null
      119-34-6
    • ~%
    • In-stock
      4-Iodo-2-nitrophenol|CS-0202570
      21784-73-6

    References

    • US2005/107339 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H317-H318-H410
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.37
  • LogP   1.905
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Iodo-2-nitrophenol sigma4-Iodo-2-nitrophenol manufacturer4-Iodo-2-nitrophenol price4-Iodo-2-nitrophenol structure4-Iodo-2-nitrophenol SDSbuy 4-Iodo-2-nitrophenol4-Iodo-2-nitrophenol supplier4-Iodo-2-nitrophenol uses4-Iodo-2-nitrophenol molecular weightprice of 4-Iodo-2-nitrophenol4-Iodo-2-nitrophenol chemical name formula of 4-Iodo-2-nitrophenol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label