2-Amino-4-chloro-6-methylpyridine

Name: 2-Amino-4-chloro-6-methylpyridine
Brand: ChemScene
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CAS No. 36340-61-1
Cat. No. CS-W019628
Purity≥97%
MDL No.MFCD00800671

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Amino-4-chloro-6-methylpyridine|CS-W019628

Structure of 36340-61-1

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Description

2-Amino-4-chloro-6-methylpyridine features a pyridine core functionalized with an amino group at position 2, a chlorine atom at position 4, and a methyl substituent at position 6. This electron-deficient heterocycle serves as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, offering enhanced reactivity in cross-coupling and nucleophilic substitution processes under standard conditions.

Application

2-Amino-4-chloro-6-methylpyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted pyridine scaffolds. Its amino and chloro groups provide orthogonal reactivity for Suzuki-Miyaura couplings, nucleophilic substitutions, and metal-catalyzed cross-coupling transformations. The methyl group enhances metabolic stability and modulates electronic properties, while the compound exhibits excellent bench stability and ease of purification, making it well-suited for scalable laboratory applications.

General Information

CAS No. 36340-61-1
Cat. No. CS-W019628
Purity ≥97%
MDL No. MFCD00800671
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇ClN₂
Molecular Weight 142.59
Synonym(s) 4-Chloro-6-methylpyridin-2-amine
SMILES CC1=CC(Cl)=CC(N)=N1

Computational Chemistry Data

TPSA 38.91
LogP 1.62562
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Amino-4-chloro-6-methylpyridine

CAS No. 36340-61-1

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