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CS-W001157 4
Total: USD 88.00

DH03

  • CAS No. 361162-95-0

  • Cat. No. CS-0001860
  • Molecule weight356.78
  • Purity≥97%
  • MDL No.MFCD09284738

*For research and further manufacturing use only, not for direct human use.

DH03|CS-0001860

Structure of 361162-95-0

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General Information

  • CAS No. 361162-95-0
  • Cat. No. CS-0001860
  • Purity ≥97%
  • MDL No. MFCD09284738
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₄ClFN₄O
  • Molecular Weight 356.78
  • Synonym(s) 6-Amino-4-[(3-chloro-4-fluorophenyl)amino]-7-ethoxyquinoline-3-carbonitrile
  • SMILES N#CC1=C(NC2=CC(Cl)=C(F)C=C2)C(C(N=C1)=C3)=CC(N)=C3OCC

Synthesis

  • Route1
    • null|null
      1313378-64-1
    • ~97%
    • DH03|CS-0001860
      361162-95-0

    References

    • US2005/65181 A1, ; Page/Page column 4 ;
  • Route2
    • 4-Fluoro-3-chloroaniline Gefitinib Impurity|CS-0229026
      367-21-5
    • ~%
    • DH03|CS-0001860
      361162-95-0

    References

    • Journal of Medicinal Chemistry, , vol. 46, # 1 p. 49 - 63
  • Route3
    • 5-Methoxy-2-methyl-4-nitroaniline|CS-0128595
      106579-00-4
    • ~%
    • DH03|CS-0001860
      361162-95-0

    References

    • Journal of Medicinal Chemistry, , vol. 46, # 1 p. 49 - 63

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H320
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362

Quality Control

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Computational Chemistry Data

  • TPSA   83.96
  • LogP   5.04528
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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