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CS-W001157 4
Total: USD 88.00

1-Boc-4-(Aminomethyl)piperidine hydrochloride

  • CAS No. 359629-16-6

  • Cat. No. CS-W020212
  • Purity≥97%
  • MDL No.MFCD03093510

*For research and further manufacturing use only, not for direct human use.

1-Boc-4-(Aminomethyl)piperidine hydrochloride|CS-W020212

Structure of 359629-16-6

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General Information

  • CAS No. 359629-16-6
  • Cat. No. CS-W020212
  • Purity ≥97%
  • MDL No. MFCD03093510
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₃ClN₂O₂
  • Molecular Weight 250.77
  • Synonym(s) None
  • SMILES Cl.O=C(OC(C)(C)C)N1CCC(CN)CC1

Description

1-Boc-4-(Aminomethyl)piperidine hydrochloride features a protected amine handle ideal for late-stage functionalization in peptide and small-molecule synthesis. The Boc group ensures stability during storage and handling, while the piperidine core provides a rigid, nitrogen-rich scaffold. This compound integrates efficiently into diverse synthetic routes under standard conditions.

Application

1-Boc-4-(aminomethyl)piperidine hydrochloride serves as a versatile building block for the synthesis of piperidine-based pharmaceutical intermediates. The Boc-protected amine enables orthogonal functionalization, while the pendant primary amine facilitates conjugation reactions. Its crystalline form ensures ease of handling and purification, with good stability under standard bench conditions. Widely used in medicinal chemistry campaigns, it functions as a key scaffold component in the construction of bioactive heterocycles and target-directed molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   2.014
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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