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CS-W001157 4
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methyl 3-amino-2-hydroxybenzoate

  • CAS No. 35748-34-6

  • Cat. No. CS-W000705
  • Purity≥96%
  • MDL No.MFCD09842614

*For research and further manufacturing use only, not for direct human use.

methyl 3-amino-2-hydroxybenzoate|CS-W000705

Structure of 35748-34-6

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General Information

  • CAS No. 35748-34-6
  • Cat. No. CS-W000705
  • Purity ≥96%
  • MDL No. MFCD09842614
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) Benzoic acid,3-aMino-2-hydroxy-, Methyl ester
  • SMILES COC(=O)c1cccc(c1O)N

Description

Methyl 3-amino-2-hydroxybenzoate features a strategically positioned amino group and hydroxyl moiety on the aromatic ring, enabling dual functionality in synthetic transformations. This ortho-substituted ester exhibits enhanced solubility in polar solvents and stability under standard bench conditions, facilitating its use in medicinal chemistry scaffolds and peptide conjugation workflows.

Application

Methyl 3-amino-2-hydroxybenzoate serves as a versatile building block in medicinal chemistry, enabling access to bioactive heterocycles and pharmaceutical intermediates. Its ortho-dihydroxyamino substitution pattern supports diverse functionalization, including electrophilic aromatic substitution and metal-catalyzed coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.761
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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