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CS-W001157 4
Total: USD 88.00

3-Bromo-5-nitrobenzaldehyde

  • CAS No. 355134-13-3

  • Cat. No. CS-W012968
  • Purity≥97%
  • MDL No.MFCD00100097

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-nitrobenzaldehyde|CS-W012968

Structure of 355134-13-3

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General Information

  • CAS No. 355134-13-3
  • Cat. No. CS-W012968
  • Purity ≥97%
  • MDL No. MFCD00100097
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrNO₃
  • Molecular Weight 230.02
  • Synonym(s) benzaldehyde, 3-bromo-5-nitro-; 3-Bromo-5-nitrobenzaldehyde
  • SMILES BrC1=CC(=CC(=C1)C=O)[N+](=O)[O-]

Description

3-Bromo-5-nitrobenzaldehyde features a bromine substituent and a nitro group positioned ortho to the aldehyde, creating a highly electron-deficient aromatic ring. This combination enhances reactivity in cross-coupling processes and enables direct functionalization in synthetic sequences requiring strong electrophilic character.

Application

3-Bromo-5-nitrobenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization via palladium-catalyzed cross-coupling reactions due to its bromo and aldehyde functionalities. The nitro group enhances electrophilicity at the ortho position, facilitating nucleophilic substitution or directed metalation. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for constructing complex heterocycles and pharmaceutical intermediates under standard reaction conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H317-H319-H335
Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   60.21
  • LogP   2.1698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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