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CS-W001157 4
Total: USD 88.00

N1,N2-Dibenzyloxalamide

  • CAS No. 3551-78-8

  • Cat. No. CS-0270015
  • Purity≥98%
  • MDL No.MFCD00022012

*For research and further manufacturing use only, not for direct human use.

N1,N2-Dibenzyloxalamide|CS-0270015

Structure of 3551-78-8

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General Information

  • CAS No. 3551-78-8
  • Cat. No. CS-0270015
  • Purity ≥98%
  • MDL No. MFCD00022012
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₆N₂O₂
  • Molecular Weight None
  • Synonym(s) N,N'-dibenzylethanediamide
  • SMILES C1=CC=C(C=C1)CNC(=O)C(=O)NCC2=CC=CC=C2

Application

N1,N2-Dibenzyloxalamide serves as a stable, bench-friendly synthon for oxalamide-based scaffolds, enabling efficient construction of biologically relevant heterocycles and peptide mimetics. Its dual benzyl protection offers orthogonal deprotection compatibility, facilitating sequential functionalization in complex molecule synthesis. The compound exhibits excellent solubility and purification ease, making it well-suited for iterative coupling strategies in medicinal chemistry campaigns.

Synthesis

  • Route1
    • null|null
      20836-96-8
    • ~93%
    • In-stock
      N1,N2-Dibenzyloxalamide|CS-0270015
      3551-78-8

    References

    • Kim, Yong Hae; Chung, Bong Chul; Chang, Hae Sung Tetrahedron Letters, 1985 , vol. 26, # 8 p. 1079 - 1082
  • Route2
    • null|null
      64481-53-4
    • ~0%
    • In-stock
      N1,N2-Dibenzyloxalamide|CS-0270015
      3551-78-8
    • null|null
      76952-19-7

    References

    • Hoare, John H.; Yates, Peter Heterocycles, 1981 , vol. 15, # 1 p. 281 - 284
  • Route3
    • null|null
      201230-82-2
    • null|null
      100-46-9
    • ~12%
    • In-stock
      N1,N2-Dibenzyloxalamide|CS-0270015
      3551-78-8
    • In-stock
      1,3-Dibenzylurea|CS-0149842
      1466-67-7

    References

    • Chiarotto, Isabella; Feroci, Marta Journal of Organic Chemistry, 2003 , vol. 68, # 18 p. 7137 - 7139

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   58.2
  • LogP   1.6192
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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