Pyridine-3,5-diol

Name: Pyridine-3,5-diol
Brand: ChemScene
Availability: InStock
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CAS No. 3543-02-0
Cat. No. CS-W002833
Purity≥97%
MDL No.MFCD01860225

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 3543-02-0

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Description

Pyridine-3,5-diol features two hydroxyl groups positioned at the 3- and 5-positions of the pyridine ring, creating a rigid, electron-rich scaffold. This configuration enhances solubility in polar solvents and supports strong hydrogen bonding, enabling its use as a directing group in transition metal catalysis. The molecule exhibits bench-stable behavior under standard conditions, facilitating integration into complex synthetic sequences without requiring inert atmosphere handling.

Application

Pyridine-3,5-diol serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling direct functionalization at both C3 and C5 positions due to its symmetric diol substitution. The molecule exhibits robust bench stability and facilitates efficient transition-metal-catalyzed cross-coupling reactions. Its dual hydroxyl groups provide orthogonal handles for derivatization, enhancing utility in the construction of heterocyclic scaffolds and bioactive molecules.

General Information

CAS No. 3543-02-0
Cat. No. CS-W002833
Purity ≥97%
MDL No. MFCD01860225
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅NO₂
Molecular Weight 111.10
Synonym(s) 3,5-Dihydroxypyridine
SMILES Oc1cncc(c1)O

Computational Chemistry Data

TPSA 53.35
LogP 0.4928
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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Pyridine-3,5-diol

CAS No. 3543-02-0

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