Boc-Cycloleucine

Name: Boc-Cycloleucine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 35264-09-6
Cat. No. CS-W007993
Purity≥98%
MDL No.MFCD01076126

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HazMat Fee

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The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Boc-cycloleucine delivers a protected cycloleucine scaffold for peptide synthesis, featuring enhanced stability and compatibility with standard coupling protocols. This bench-stable building block integrates seamlessly into peptidomimetic architectures, enabling efficient access to constrained cyclic motifs in bioactive molecule design.

Application

Boc-cycloleucine serves as a stable, bench-ready building block for the synthesis of cycloleucine-containing peptides and heterocyclic scaffolds. Its tert-butoxycarbonyl group enables straightforward N-terminal protection during solid-phase peptide synthesis, while the cycloleucine core provides conformational rigidity beneficial for structure-activity studies. The derivative exhibits excellent functional group tolerance and facilitates efficient coupling reactions under standard conditions.

General Information

CAS No. 35264-09-6
Cat. No. CS-W007993
Purity ≥98%
MDL No. MFCD01076126
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₉NO₄
Molecular Weight 229.27
Synonym(s) N-Boc-cycloleucine
SMILES O=C(C1(NC(OC(C)(C)C)=O)CCCC1)O

Computational Chemistry Data

TPSA 75.63
LogP 1.9085
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Boc

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Fatty ring compounds Cyclopentane compounds

Life Science Amino Acids and their Derivatives N-protected amino acid

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Boc-Cycloleucine

CAS No. 35264-09-6

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