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CS-W001157 4
Total: USD 88.00

N-(4-Methoxybenzyl)aniline

  • CAS No. 3526-43-0

  • Cat. No. CS-0150388
  • Purity≥95%
  • MDL No.MFCD00025831

*For research and further manufacturing use only, not for direct human use.

N-(4-Methoxybenzyl)aniline|CS-0150388

Structure of 3526-43-0

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General Information

  • CAS No. 3526-43-0
  • Cat. No. CS-0150388
  • Purity ≥95%
  • MDL No. MFCD00025831
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₅NO
  • Molecular Weight 213.28
  • Synonym(s) (4-METHOXY-BENZYL)-PHENYL-AMINE
  • SMILES COC1=CC=C(C=C1)CNC2=CC=CC=C2

Description

N-(4-Methoxybenzyl)aniline features a benzyl-linked aniline scaffold with a para-methoxy substituent that enhances solubility and electron donation. This stable, bench-ready amine integrates readily into C–N coupling reactions and serves as a key intermediate in the synthesis of bioactive heterocycles and functional materials.

Application

N-(4-Methoxybenzyl)aniline serves as a versatile building block in medicinal chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. Its benzylic amine functionality exhibits excellent stability and compatibility with standard coupling protocols, while the para-methoxy group enhances solubility and modulates electronic properties. The molecule facilitates straightforward deprotection and functionalization, making it well-suited for iterative synthesis workflows and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335-H400
Precautionary Statements : P261-P273-P280

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   3.3073
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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