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CS-W001157 4
Total: USD 88.00

Azetidin-3-ol hydrochloride

  • CAS No. 18621-18-6

  • Cat. No. CS-D0673
  • Purity≥97%
  • MDL No.MFCD02683887

*For research and further manufacturing use only, not for direct human use.

Azetidin-3-ol hydrochloride|CS-D0673

Structure of 18621-18-6

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General Information

  • CAS No. 18621-18-6
  • Cat. No. CS-D0673
  • Purity ≥97%
  • MDL No. MFCD02683887
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₈ClNO
  • Molecular Weight 109.55
  • Synonym(s) None
  • SMILES OC1CNC1.Cl

Description

Building block used in a recent synthesis of a fluoroquinolone antibiotic.

Synthesis

  • Route1
    • 1-Benzhydryl-3-azetidinol hydrochloride|CS-W002514
      90604-02-7
    • ~99%
    • In-stock
      Azetidin-3-ol hydrochloride|CS-D0673
      18621-18-6

    References

    • Isoda, Takeshi; Ushirogochi, Hideki; Satoh, Koichi; Takasaki, Tsuyoshi; Yamamura, Itsuki; Sato, Chisato; Mihira, Ado; Abe, Takao; Tamai, Satoshi; Yamamoto, Shigeki; Kumagai, Toshio; Nagao, Yoshimitsu Journal of Antibiotics, 2006 , vol. 59, # 4 p. 241 - 247
  • Route2
    • null|null
      7647-01-0
    • In-stock
      1-Benzhydrylazetidin-3-ol|CS-D0677
      18621-17-5
    • ~67%
    • In-stock
      Azetidin-3-ol hydrochloride|CS-D0673
      18621-18-6

    References

    • Adams, Jerry L.; Boehm, Jeffrey C.; Hall, Ralph; Jin, Qi; Kasparec, Jiri; Silva, Domingos J.; Taggart, John J. Patent: US2004/116697 A1, 2004 ; Location in patent: Page 82 ; US 20040116697 A1
  • Route3
    • 1-Benzylazetidin-3-ol|CS-W002713
      54881-13-9
    • ~%
    • In-stock
      Azetidin-3-ol hydrochloride|CS-D0673
      18621-18-6

    References

    • WO2006/15194 A2, ; Page/Page column 14 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.6277
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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