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CS-W001157 4
Total: USD 88.00

(3-Chloro-2-fluorophenyl)boronic acid

  • CAS No. 352535-82-1

  • Cat. No. CS-W017487
  • Purity≥98%
  • MDL No.MFCD05664224

*For research and further manufacturing use only, not for direct human use.

(3-Chloro-2-fluorophenyl)boronic acid|CS-W017487

Structure of 352535-82-1

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General Information

  • CAS No. 352535-82-1
  • Cat. No. CS-W017487
  • Purity ≥98%
  • MDL No. MFCD05664224
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BClFO₂
  • Molecular Weight None
  • Synonym(s) 3-Chloro-2-fluorophenylboronic acid
  • SMILES FC1=C(Cl)C=CC=C1B(O)O

Application

(3-Chloro-2-fluorophenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient carbon-carbon bond formation under mild conditions. Its ortho-halogenated aryl boronic ester functionality offers enhanced stability and predictable reactivity, facilitating the synthesis of complex biaryl scaffolds common in pharmaceutical and agrochemical development. The compound exhibits good bench stability, ease of handling, and compatibility with diverse functional groups, making it a reliable choice for iterative synthetic campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.1589
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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