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CS-W001157 4
Total: USD 88.00

(2-Fluoro-5-formylphenyl)boronic acid

  • CAS No. 352534-79-3

  • Cat. No. CS-W016044
  • Purity≥98%
  • MDL No.MFCD03095100

*For research and further manufacturing use only, not for direct human use.

(2-Fluoro-5-formylphenyl)boronic acid|CS-W016044

Structure of 352534-79-3

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General Information

  • CAS No. 352534-79-3
  • Cat. No. CS-W016044
  • Purity ≥98%
  • MDL No. MFCD03095100
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BFO₃
  • Molecular Weight 167.93
  • Synonym(s) Boronic acid, B-(2-fluoro-5-formylphenyl)-
  • SMILES OB(O)C1=C(F)C=CC(C=O)=C1

Description

This boronate moiety integrates a fluorinated aryl scaffold with a formyl handle, enabling selective coupling in late-stage functionalization. The electron-deficient ring enhances reactivity in Suzuki-Miyaura transformations, while the bench-stable boronic acid functionality simplifies handling under standard conditions.

Application

(2-Fluoro-5-formylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The ortho-fluoro and formyl groups provide orthogonal reactivity for downstream functionalization, including nucleophilic substitution and condensation reactions. Its bench-stable nature and compatibility with diverse reaction environments make it ideal for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   -0.682
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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