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3-Hydroxy-8-methoxy-6H-benzo[c]chromen-6-one

  • CAS No. 35233-17-1

  • Cat. No. CS-0316096
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-8-methoxy-6H-benzo[c]chromen-6-one|CS-0316096

Structure of 35233-17-1

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General Information

  • CAS No. 35233-17-1
  • Cat. No. CS-0316096
  • Purity ≥95%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₀O₄
  • Molecular Weight 242.23
  • Synonym(s) Urolithin A 8-Methyl Ether
  • SMILES COC1=CC2=C(C=C1)C3=C(C=C(C=C3)O)OC2=O

Description

This coumarin derivative features a hydroxyl group at the 3-position and a methoxy substituent at the 6-position, conferring enhanced solubility and stability. The fused chromenone core supports diverse synthetic applications in medicinal chemistry and fluorescent probe development.

Application

3-Hydroxy-8-methoxy-6H-benzo[c]chromen-6-one serves as a versatile scaffold in natural product synthesis and medicinal chemistry, enabling efficient access to coumarin-based architectures. Its ortho-hydroxyl and methoxy substituents facilitate regioselective functionalization, while the quinone-like core supports electrophilic substitution and transition-metal-catalyzed coupling reactions. The compound exhibits bench stability and compatibility with standard purification protocols, making it a practical building block for drug discovery campaigns involving fused heterocyclic systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P363-P501

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Computational Chemistry Data

  • TPSA   59.67
  • LogP   2.6604
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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