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CS-W001157 4
Total: USD 88.00

Quinoline-8-sulfonamide

  • CAS No. 35203-91-9

  • Cat. No. CS-0155801
  • Purity≥98%
  • MDL No.MFCD01191906
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Quinoline-8-sulfonamide|CS-0155801

Structure of 35203-91-9

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Description

Quinoline-8-sulfonamide features a rigid heteroaromatic core paired with a sulfonamide group at the C8 position, enabling strong hydrogen bonding and enhanced solubility. This scaffold integrates readily into medicinal chemistry libraries, offering favorable pharmacokinetic properties and serving as a key building block for kinase inhibitors and antimicrobial agents.

Application

Quinoline-8-sulfonamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through well-established coupling reactions. Its sulfonamide group exhibits favorable solubility and hydrogen-bonding capacity, enhancing target engagement potential. The quinoline scaffold provides metabolic stability and facilitates π–π stacking interactions in biological targets. This compound demonstrates robust bench stability and compatibility with standard purification protocols, making it a practical choice for lead optimization campaigns.

General Information

  • CAS No. 35203-91-9
  • Cat. No. CS-0155801
  • Purity ≥98%
  • MDL No. MFCD01191906
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂S
  • Molecular Weight 208.24
  • Synonym(s) 8-Quinolinesulfonamide
  • SMILES C1=CC2=C(C(=C1)S(=O)(=O)N)N=CC=C2

Computational Chemistry Data

  • TPSA   73.05
  • LogP   0.8822
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

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