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Structure of 351990-51-7
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5-Nitro-1H-imidazole-2-carboxylic acid features a conjugated imidazole core bearing both a nitro group at the 5-position and a carboxylic acid at the 2-position, enabling versatile functionalization. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced solubility and metabolic stability in drug discovery applications.
5-Nitro-1H-imidazole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of imidazole-based heterocycles through standard coupling and functional group interconversions. Its nitro and carboxylic acid groups provide orthogonal reactivity for late-stage modifications, facilitating access to diverse scaffolds. The compound exhibits good bench stability and is amenable to purification via recrystallization, supporting reliable use in scale-up and high-throughput workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: