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Structure of 349552-70-1
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Methyl 1-chloroisoquinoline-3-carboxylate features a chlorinated isoquinoline core with a methyl ester at the 3-position, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient ring system supports transition-metal-catalyzed couplings, while the ester group offers versatility in downstream functionalization. This bench-stable reagent facilitates efficient access to bioactive isoquinoline derivatives under standard conditions.
Methyl 1-chloroisoquinoline-3-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient functionalization at the C-1 position of isoquinoline scaffolds. Its chloro group facilitates palladium-catalyzed cross-coupling reactions, while the ester functionality allows for selective reduction or hydrolysis. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: