Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 6-chloropyrazine-2-carboxylate

  • CAS No. 23611-75-8

  • Cat. No. CS-W003732
  • Purity≥98%
  • MDL No.MFCD10686598

*For research and further manufacturing use only, not for direct human use.

Methyl 6-chloropyrazine-2-carboxylate|CS-W003732

Structure of 23611-75-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 23611-75-8
  • Cat. No. CS-W003732
  • Purity ≥98%
  • MDL No. MFCD10686598
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅ClN₂O₂
  • Molecular Weight 172.57
  • Synonym(s) Methyl 6-chloro-2-pyrazinecarboxylate
  • SMILES COC(=O)c1cncc(n1)Cl

Description

Suitable for fluorescent labellingRhodamine B is used as a laser dye, metal chelating agent and an additive to drugs and cosmetics. It also serves as a staining fluorescent dye, which is used as a colorant in inks, paper and plastics. Further, it is used to make pink fluorescent pigments. It is also employed as a biomarker in oral rabies vaccines for wildlife such as raccoons. In addition to this, it is a useful fluorochrome for histology, fluorescence resonance energy transfer (FRET) and mitochondrial probe.

Application

Methyl 6-chloropyrazine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrazine-based pharmacophores. The chloro group at the C6 position facilitates palladium-catalyzed cross-coupling reactions, while the ester functionality supports selective transformations. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for modular synthesis of heterocyclic scaffolds relevant to drug discovery.

Synthesis

  • Route1
    • null|null
      770-00-3
    • ~67%
    • In-stock
      Methyl 6-chloropyrazine-2-carboxylate|CS-W003732
      23611-75-8

    References

    • Scanio, Marc J. C.; Shi, Lei; Bunnelle, William H.; Anderson, David J.; Helfrich, Rosalind J.; Malysz, John; Thorin-Hagene, Kirsten K.; Van Handel, Ceclia E.; Marsh, Kennan C.; Lee, Chih-Hung; Gopalakrishnan, Murali Journal of Medicinal Chemistry, 2011 , vol. 54, # 21 p. 7678 - 7692
  • Route2

    References

    • Matthews, Hayden; Ranson, Marie; Tyndall, Joel D.A.; Kelso, Michael J. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 22 p. 6760 - 6766
  • Route3
    • null|null
      85661-24-1
    • ~%
    • In-stock
      Methyl 3-chloropyrazine-2-carboxylate|CS-W019277
      27825-21-4
    • In-stock
      Methyl 6-chloropyrazine-2-carboxylate|CS-W003732
      23611-75-8

    References

    • Journal of Chemical Research, Miniprint, , # 10 p. 2860 - 2875

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.08
  • LogP   0.9166
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Methyl 6-chloropyrazine-2-carboxylate sigmaMethyl 6-chloropyrazine-2-carboxylate manufacturerMethyl 6-chloropyrazine-2-carboxylate priceMethyl 6-chloropyrazine-2-carboxylate structureMethyl 6-chloropyrazine-2-carboxylate SDSbuy Methyl 6-chloropyrazine-2-carboxylateMethyl 6-chloropyrazine-2-carboxylate supplierMethyl 6-chloropyrazine-2-carboxylate usesMethyl 6-chloropyrazine-2-carboxylate molecular weightprice of Methyl 6-chloropyrazine-2-carboxylateMethyl 6-chloropyrazine-2-carboxylate chemical name formula of Methyl 6-chloropyrazine-2-carboxylate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label