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CS-W001157 4
Total: USD 88.00

5,6,7,8-Tetrahydro-1,6-naphthyridine dihydrochloride

  • CAS No. 348623-30-3

  • Cat. No. CS-W005893
  • Purity≥95%
  • MDL No.MFCD09997813

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-Tetrahydro-1,6-naphthyridine dihydrochloride|CS-W005893

Structure of 348623-30-3

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General Information

  • CAS No. 348623-30-3
  • Cat. No. CS-W005893
  • Purity ≥95%
  • MDL No. MFCD09997813
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂Cl₂N₂
  • Molecular Weight 207.10
  • Synonym(s) 5,6,7,8-Tetrahydro-1,6phthyridine dihydrochloride
  • SMILES C1(C=CC=N2)=C2CCNC1.Cl.Cl

Description

5,6,7,8-Tetrahydro-1,6-naphthyridine dihydrochloride is a bench-stable, moisture-tolerant heterocyclic base featuring a saturated naphthyridine core. This dihydrochloride salt enhances solubility in aqueous and polar organic media, enabling efficient incorporation into synthetic sequences. The protonated form facilitates salt formation for purification and handling, streamlining use in medicinal chemistry workflows.

Application

5,6,7,8-Tetrahydro-1,6-naphthyridine dihydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to nitrogen-containing scaffolds. Its stable, crystalline form facilitates handling and purification, while the protonated pyridine nitrogen enhances solubility and reactivity in nucleophilic substitution and coupling reactions. Functions effectively as a synthetic intermediate in the construction of bioactive molecules and API candidates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   1.5709
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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