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Structure of 34632-69-4
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Ethyl 4-chloroquinazoline-2-carboxylate features a chlorinated quinazoline core that enables direct functionalization at the C4 position. This electron-deficient heterocycle integrates readily into synthetic sequences requiring robust, polarizable scaffolds. The ester group enhances solubility and facilitates downstream transformations.
Ethyl 4-chloroquinazoline-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to quinazoline-based scaffolds. The chloro substituent at the C4 position facilitates nucleophilic substitution reactions, while the ester group supports subsequent transformations such as hydrolysis or coupling. Its bench-stable nature and compatibility with standard cross-coupling protocols make it well-suited for the synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: