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Structure of 34522-72-0
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5,7-Difluoroquinoline is a fluorinated heterocycle featuring two strategically positioned fluorine atoms that enhance electron deficiency and influence reactivity in cross-coupling processes. This bench-stable compound integrates readily into synthetic scaffolds requiring strong electron-withdrawing character, offering improved solubility and stability under standard conditions.
5,7-Difluoroquinoline serves as a versatile building block in medicinal chemistry, enabling direct functionalization at electron-deficient positions via palladium-catalyzed cross-coupling. Its difluoro substitution enhances metabolic stability and modulates electronic properties, facilitating integration into bioactive scaffolds. The compound exhibits excellent bench stability, clean reaction profiles, and compatibility with standard purification methods, making it well-suited for iterative synthesis and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: